FINAL INTERNATIONAL ISO/FDIS DRAFT 22590 STANDARD ISO/TC249 Traditional Chinese medicine Secretariat:SAC Determination of sulfur dioxide in Voting begins on: natural products by titration 2020-06-01 Votingterminateson: Medecinetraditionnellechinoise-Dosagedudioxydede soufredans 2020-07-27 les produits naturels par titrage RECIPIENTS OF THIS DRAFT ARE INVITED TO SUBMIT, WITH THEIR COMMENTS, NOTIFICATION OF ANY RELEVANT PATENT RIGHTS OF WHICH THEY ARE AWARE AND TO PROVIDE SUPPORTING DOCUMENTATION. INADDITION TOTHEIR EVALUATION AS Reference number BEING ACCEPTABLE FOR INDUSTRIAL, TECHNO- IS0/FDIS22590:2020(E) LOGICAL, COMMERCIAL AND USER PURPOSES, DRAFT INTERNATIONAL STANDARDS MAY ON [So OCCASION HAVE TO BE CONSIDERED IN THE LIGHT OF THEIR POTENTIAL TO BECOME STAN- DARDS TO WHICH REFERENCE MAY BE MADE IN @IS0 2020 NATIONAL REGULATIONS. IS0/FDIS22590:2020(E) COPYRIGHTPROTECTEDDOCUMENT IS02020 All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting below or Iso's member body in the country of the requester. ISO copyright office CP 401 : Ch. de Blandonnet 8 CH-1214 Vernier, Geneva Phone:+4122749 0111 Fax: +41 22 749 09 47 Email: copyright@iso.org Website: www.iso.org Published in Switzerland ii @ IS0 2020 - All rights reserved IS0/FDIS22590:2020(E) Contents Page Foreword ..iv 1 Scope .1 2 Normativereferences 3 Terms anddefinitions 4 Apparatus .2 5 Reagents. ..2 6 Samplingandpreservationofsamples .2 6.1 Sampling .2 6.1.1 Laboratory samples. 2 6.1.2 Sample identification 2 6.2 Samplepre-treatmentandpreservation .3 6.2.1 Samplepre-treatment .3 6.2.2 Sample storage .3 Test method .3 7 7.1 Test procedure .3 7.2 Calculation 4 Annex A (informative) Reference of national, regional and organizational limits of suifur dioxide in food and natural products of traditional Chinese medicine and calculated limits using target hazard quotients based on USEPA and WHO 6 AnnexB (informative)Gas chromatography-Determination of sulfur dioxide in natural traditional Chinesemedicine materials. 9 Annex C (informative) Analysis of the similarities and differences of acid-base titration indifferentcountries 10 Bibliography .13 IS0 2020-All rights reserved ili